Relationship between dialysis adequacy and cognitive function in hemodialysis patients

The prevalence of cognitive impairment is extremely high in dialysis patients, and it has been hypothesized that low urea clearance an impact on impairment. However, several other studies conducted the era high-flux have not shown association between lower Kt/V poorer function. Therefore, directly examine relationship adequacy function hemodialysis patients are essential. present study aimed to investigate functions their with adequacy.
 Methods. This cross-sectional observational included 100 healthy volunteers. Dialysis was assessed by ratio previous month. Mini-Mental State Examination (MMSE), Montreal Cognitive Assessment Test (MoCA), Clock Drawing (CDT) were used assess Multiple regression analysis determine significant assessments independent variables (Kt/V, age, education, hemoglobin, albumin).
 Results. There no differences controls age sex. Patients had a mean 1.52±0.29. MMSE, MoCA, CDT than controls. strong positive correlations MMSE (r = 0.81), MoCA 0.84), 0.79).
 Conclusion. significantly decreased compared associated adequacy. should be questioned